Endocrine Abstracts

Introduction: 5 alpha-steroid reductase deficiency (5α SRD) is a rare autosomal recessive disorder. Presented here is the clinical profile and long term outcomes of subjects with 5α SRD examined in our hospital during the last 30 yrs.Methods: Records of patients registered in the endocrine clinic of our hospital and new patients with diagnosis of 5α SRD were compiled. Details of history,physical examination,chromosomal analysis, hormonal s...

Case History: A 54 year old man with type 2 diabetes mellitus was referred in 2014 to our multi-disciplinary foot care service for the management of ulcers. One year previously he had undergone a left hallux amputation due to underlying osteomyelitis. Over the period 2015 through 2021, he required multiple admissions for management of limb threatening foot sepsis with exposed necrotic mid and hind foot bone. In 2016 he suffered a cerebrovascular infarct and in 2019 an episode ...

It is recommended that all patients with PA who are suitable for surgery should undergo adrenal CT and AVS unless there is a large unilateral adenoma with a completely normal contralateral gland. We reviewed 100 patients diagnosed with PA. AVS was performed in 93. Different lateralisation criteria for AVS were assessed using ROC curve analysis to determine the optimal one for identifying an adenoma. We reviewed the outcomes of adrenalectomy evaluating which pre-operative chara...

This presentation will review the role of nutrition in diabetes management, the evolution of advice from RD Lawrence’s Red and Black lines through to the evidence from the current era of the need to consider meal compensation as the basis for insulin dosing with food, the importance of quality of good choices on outcomes, the impact of technology on our understanding of post prandial glucose responses and insulin delivery strategies....

Aim: Individual compliance, thrombotic risks, and relief of menstrual complains are the three main components determining hormonal contraceptive choices. The aim of this survey was to see how these terms influences choices in different age groups.Material and methods: Literature survey.Results: Women generally comply well with different types of hormonal contraceptives. A minority may have trouble taking one tablet a day, and other...

Amiodarone is frequently used in cardiac patients but has side effects which effects the thyroid due to its high iodine content. The use of radioiodine in AIH with low iodine uptake is controversial. In these patients therapeutic choices for refractory cases include either: surgery, antithyroid drugs, or glucocorticosteriods.What are the treatment choices in elderly patients which can’t be operated on, agranulocytosis is present, or have toxic liver...

One of the corner stones of nutritional advice children and young people with diabetes is an awareness of how the food they choose can affect their blood glucose. Knowing; which foods contain carbohydrate, how to find this information out, how to estimate the amount of carbs and why not all carbs are the same, can help those living with diabetes, their families and careers make informed choices. Chris Cheyette is senior diabetes specialist dietitian at Kings College Hospital. ...

Bariatric or metabolic surgery, such as Roux-en-Y gastric bypass and sleeve gastrectomy are becoming increasingly prevalent as these treatments are now recommended as treatment choices for obesity and type 2 diabetes. Post-bariatric hypoglycaemia (PBH), typically a post-prandial hyperinsulinaemic hypoglycaemia occurring 1-3 hr after ingestion of food, is now more commonly encountered in practice, presenting either to endocrine/metabolic outpatient clinics or during medical on-...

Long bone fractures are common in childhood. However, recurrent fractures and certain types of fractures may indicate an underlying problem such as bone fragility. It is important to be able to identify those children who require closer evaluation and to consider how best to investigate such children. This should be done with an understanding of the likelihood and range of disease that may present with fractures, as well as the role of various modes of assessment. For those wi...

Background: Nutritional interventions are required for effective management of diabetes Mellitus. Dietary recommendations act as amajor intervention for treatment of D Mand obesity. It is recommended that the diet should be individually adapted to personal choices and metabolic goals. With advent of technology newer monitoring tools like continuous glucose monitoring systems (CGM) are now finding their way into Diabetes management and nutrition therapy. The ambulatory glucose ...