Endocrine Abstracts

Objective: To describe the clinical, aetiological and prognostic differences in diabetic and non-diabetic ischaemic stroke (IS) patients.Materials and methods: Retrospective analysis of prospective series of IS patients. Patients were classified as non-DM and DM patients. Demographic and clinical characteristics were compared between two groups. IS prognosis was evaluated by modified Rankin scale (mRS) and NIHSS (NIH stroke scale)....

Introduction: Strokes are common diabetes macrovascular complications. A good control of cardiovascular risk factors such as glycemic control has been proven to reduce the risk of its appearance. Aim: Describe diabetes prevalence in patients admitted to hospital because of a stroke, as well as their treatment and metabolic control.Patients and methods: Observational retrospective study of patients admitted to the Neurology section because of a s...

Introduction: Flash glucose monitoring (FGM) allows non-invasive glucose level assessment. Studies have shown that patients using FGM test their glucose levels more often than those who use traditional blood glucose testing. Given that a higher rate of glucose testing has showed to improve glycemic control our objective was to describe the change in the glycemic control and time in euglycemic range in patients with FGM and the effect of the number of scans in this control....

Introduction: Non-functioning pituitary adenomas (NFPAs) represent the most common pituitary tumour. They usually appear in the middle age of life, without differences between genders. Mass growth produces the first symptoms so the diagnosis is usually late. Surgery is the first-line treatment with variable success (19-83%). The objective of this study is to evaluate the symptoms, diagnosis, treatment and final state of patients with NFPAs.Methods: Obser...

Introduction: The duration of hypercortisolism in Cushing’s disease (CD) appears to be inversely related to the reversibility of complications, which in turn increase mortality. This makes it necessary to identify medical therapies capable of normalizing cortisol overproduction before transsphenoidal surgery. The aim of this study was to determine if the clinical data of patients with CD before surgery allow predicting the presence and/or abundance of somatostatin (ssts) ...

Cinacalcet decreases and normalizes serum calcium levels across a broad severity range of primary hyperparathyroidism (PHPT), slightly reduces parathyroid hormone levels which generally remains elevated, whereas it has no effect on bone mineral density (BMD). Therefore, when administering cinacalcet to a patient with PHPT, concomitant treatment with an anti-catabolic drug should be considered.An open-labeled, prospective trial was conducted in 32 patient...

Introduction: Due to the widespread use of imaging studies performed in hospitalised patients for other indications, adrenal incidentalomas (AI) are frequent findings in the everyday clinical practice. The objective of this research is to describe the prevalence of hormonally active and malignant AI.Patients and methods: Observational retrospective study of a cohort of patients who consulted in the Endocrinology service between 2005 and 2015 because of a...

Objective: The aim of this study was to assess the diagnostic accuracy of BIPSS with desmopressin stimulation in the differential diagnosis of ACTH-dependent Cushing’s syndrome.Patients and methods: Retrospective study of patients studied to our hospital for diagnosis of ACTH-dependent Cushing’s syndrome (2000–2015). The histopathological results in patients who underwent a surgical procedure was considered the reference for statistical st...

Introduction: The Bethesda System classifies suspicious thyroid nodules or those with a large size after fine-needle aspiration (FNA) depending on the risk of malignancy through its cytology study. Bethesda category 3 (B3) implies atypia of uncertain significance or follicular lesion of undetermined significance. Objectives: To determine the final diagnosis of category B3 nodules and the number of cases in which a second or third FNA results in a conclusive category (B2, B4, B...

Background: Cushing’s syndrome (CS) is considered to be more frequent among patients with metabolic syndrome. Previous studies have suggested to perform a routine screening for CS in obese patients; however, more recent reports only recommend a case-finding approach in patients with uncontrolled diabetes and hypertension, despite appropriate treatment.Objective: The aim of this study was to evaluate the prevalence of unsuspected CS in morbidly obese...