Endocrine Abstracts

Introduction: Recently, it has been suggested that thyrotropin (TSH) concentration can be used as a marker for prediction of thyroid malignancy. However, the association between the cytology results and TSH levels is not clear. In this study, we aimed to investigate the relationship between TSH levels and Bethesda categories and determine the role of TSH levels in prediction of malignancy in patients with different Bethesda categories.Methods: The data o...

Introduction: Adrenal incidentalomas are defined as adrenal lesions incidentally discovered during radiological imaging of the abdomen without prior suspicion of adrenal disease. Approximately 70% of adrenal incidentalomas are non-functional adenomas. Pheochromocytoma presents only 5–7% of the remaining functional incidentalomas. Asymptomatic pheochromocytoma-incidentaloma is usually smaller than 1 cm. Large pheochromocytoma, incidentally found, without any clinical signs...

Introduction: Incidence of diabetes mellitus worldwide is on the rise, and better methods of prevention and treatment are needed. We evaluated the possible antidiabetic effect of embryonic antitumor modulator (EATM) created by Mkrtchyan, which reportedly exhibit anticancer, neuroprotective and immunomodulatory properties.Materials and methods: Rats with streptozotocin (STZ)-induced diabetes (55 mg/kg once i.p.) were injected EATM (1 mg/200 g rat body mas...

Diabetes mellitus (DM) is associated with significant morbidity and mortality despite steadily improving standards of care. Coronary heart disease (CHD) is by far the most common cause of death in individuals with diabetes.A characteristic pattern, termed diabetic dyslipidemia, consists of specifically mild to marked elevation of triglyceride-rich lipoproteins (VLDLs) and VLDL remnants concentrations and low levels of HDL-C. Raised serum triglycerides an...

Introduction: The widespread use of abdominal ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) has led to a predictable rise in the discovery of incidental adrenal lesions, some of which will be silent pheochromocytoma. Thus, about ten en percent of pheochromocytoma cases were diagnosed incidentally.Methods: We studied retrospectively the notes of 23 patients with histologically confirmed pheochromocytom. Demographic information,...

Intratesticular testosterone levels in Klinefelter syndrome (KS) are comparable to controls and Leydig cell function was proven to be normal at least in vitro, testicular vascularization changes came into focus as a potential factor contributing to hypogonadism. We performed enhanced ultrasound based analysis of the testicular blood support in our 41,XXY* mice. Adult male 41,XXY* (n=5) and control mice (n=6) underwent ultrasound...

Background: Insulin-like growth factor-1 (IGF-1) is known to be closely related to the growth of thyroid cells and thyroid diseases. However, the association between IGF-1, thyroid nodule, and thyroid cancer has not been clearly established yet. Therefore, this study investigated the association between IGF-1 and thyroid nodule size.Methods: A total of 346 patients with thyroid nodules confirmed by ultrasonography were included. For all participants, the...

Objectives: To define sonographic and color Doppler peculiarities of thyroid nodules influencing the efficacy and follow-up principles of percutaneous laser ablation (PLA).Methods: Three hundred forty-five thyroid nodules were treated with 1–3 PLA sessions and subsequently sonographically examined every three months within one year. Indication for PLA was increase sizes of nodules. All nodes were benign according to FNAB.Resul...

Background: Amiodarone is an antiarrhytmic drug used mainly in atrial fibrillation. Amiodarone-induced thyrotoxicosis (AIT) is less common than hypothyroidism, but it represents a true therapeutic challenge. AIT can be due iodine load (type 1) or a destructive thyroiditis (type 2).Methods: Retrospective study of patients with AIT, diagnosed between 2010 and 2015, in a central hospital. We reviewed medical records regarding age, gender, amiodarone therapy...

In our centre, thyroid core-biopsy (CB) has replaced fine needle aspiration biopsy (FNAB) in the study of thyroid nodules because its better accuracy. International guidelines recommend repeating the FNA in cases of inadequate or insufficient first specimen, but nothing is published about the case in failed CB.Objective: To study the differences between nodules with inadequate and diagnostic thyroid Core Biopsy and the accuracy of repeating a CB after a ...