Endocrine Abstracts

Aim: A key diagnostic step to determine the cause of hyperthyroidism is the measurement of circulating thyroid-stimulating immunoglobulin (TSI). High levels are associated with Graves’ disease (GD). A thyroid scintigraphy (TRS) is recommended when TSI is absent or its measurement unavailable, as TRS is capable of differentiating between GD (diffuse uptake) and toxic goitre (TG) (patchy uptake). Nevertheless, and while rarely necessary, histopathology remain the best metho...

Background: Serotonin production by ileum neuroendocrine tumors (i-NETs) is considered a critical mediator of the fibrotic reaction in mesenteric mass (MM)/ lymph node metastasis. Antidepressants modify serotonin dynamics: however, their role in MM formation is uncertain. We hypothesized that histories of antidepressant use affect MM formation. This study examined the correlation between antidepressant use and MM formation.Methods: One hundred eighty-two...

Background: Testosterone therapy (TTh) may produce various side effects, particularly erythrocytosis, with short-acting testosterone (T) injections presenting the greatest risk. Other causes are smoking and obesity. Erythrocytosis increases blood viscosity, which may lead to thromboembolic complications. Aim: to study the frequency of erythrocytosis induced by TTh and its predictive factors on transgender males (TM) in the Gender Unit of our hospital.Met...

Introduction: Obesity is known to be a disease of civilization. Both genetic and environmental factors play a role in the development of obesity. In the vast majority of cases, the main factor is eating disorders and hypodynamy. The modern human exceeds daily food demand mainly due to saturated fats and refined carbohydrates, with lack of fibre and vitamin. We decided to test the source of folic acid, because this vitamin is part of the folate cycle as a coenzyme to reduce hom...

Introduction: Persons with diabetes may need to be hospitalized in order to improve diabetes balance. We aimed to evaluate the benefits from hospitalization in a diabetes department on glycemic parameters.Method: It was a descriptive cross-sectional study conducted on diabetic patients consulting for the first time after a hospitalization in the department (C) of the National Institute of Nutrition of Tunis for the management of a poorly controlled diabe...

Parvovirus (Erythrovirus) B19 (EVB19) infection may trigger autoimmune diseases like SLE, RA, and vasculitis. Parvovirus B19 belongs to the parvoviridae family and to the erythrovirus genus. The etiopathogenesis of autoimmune diabetes mellitus could not been explained yet. The aim of our study was to investigate whether EVB19 may have a role in the etiopathogenesis of type 1 DM. Therefore have we examined whether EVB19 is more frequent among type 1 diabetics. 32 patients with ...

Status of carbohydrate metabolism in patients with primary hyperparathyroidism (PGPT) has been studied extensively in recent years, but the results of studies on the impact of long-term elevated levels of parathyroid hormone and hypercalcemia on the risk of type 2 diabetes continues to be in the discussion.Objective: To study is to examine the prevalence of type 2 diabetes in patients with manifested and asymptomatic PGPT.Materials...

Aim: To study the frequency of growth hormone deficiency (GHD) in patients with nonfunctional pituitary tumors (NFPA).Materials and methods: Over a period of 1.0 year, we studied in our department retrospective data of 33 patients with pituitary tumors in terms of CT/MRI imaging and detailed hormonal functional assessment – STH, IGF-1, LH, FSH, ACTH, prolactin, TSH, cortisol, thyroxine. From the patients are 11 – men and 12 women, mean age of p...

Objective: To examine the association between severity of diabetic peripheral neuropathy and depressive symptoms and investigated the potential mediators of this association.Materials and methods: The Hospital Anxiety and Depression Scale (HADS) was used to assess depressive symptoms in 492 patients (mean age 62 years; 70% male; 72% type 2 diabetic) with diabetic neuropathy diagnosed by the Neuropathy Disability Score (NDS) and the Vibration Perception T...

Introduction: Improvement of health related quality of life (QoL) is one of the main goals defined by the WHO and besides reduction of mortality and morbidity an important objective for health outcomes. In chronic endocrine diseases, QoL often remains impaired despite cure or remission of the disease. In quantitative analyses, factors such as age, gender, BMI and depression, are associated with reduced QoL. However, aspects of social interaction and more complex individual con...