Endocrine Abstracts

The silent myocardial ischemia is a serious diagnostic problem especially in patients with long-standing diabetes of type 1 (DM). Resting as well as exercise myocardial perfusion scintigraphy tests allow to recognize the silent myocardial ischemia in these groups of patients and to start the relevant treatment. The aim of the study was to establish the prevalence of myocardial ischemia in patients with type 1 DM, without clinical symptoms of ischemic heart disease (IHD) and wi...

Aim: To ascertain the types of treatment, results and correlation between GH and the simultaneous IGF-1. Setting: Endocrine and Neurosurgical Unit. Methods: Endocrine and laboratory database of 17 acromegalic patients (11 male) with mean (SD) age 51(3) years and follow up 11 years. Results: Pituitary surgery 11 patients (3 twice), external radiotherapy 10 (one heavy particle therapy). GH levels have come down from a median value 32.5 mU per litre (Mean plus/minus SEM: 51.9 plu...

IntroductionObesity is an important medical and social problem of our time, because its prevalence is growing rapidly and affects about 30% of the adult population of the planet. Obesity is characterized by an increase in the expression of cytokines that cause endothelial damage. It is known that prohormone thyroxine (T4) is converted into 5 times more active triiodothyronine (T3) in peripheral organs (such as live...

IntroductionThyroid autoantibodies can detected in many disorders not only at the Hosimoto autoimmune thyroiditis. Their level and frequency may vary depending on many factors both thyroidal and nonthyroidal. Anti thyroid peroxidase autoantibodies (ATPO) is one of the well known among them. We analysed frequencies of higher level of ATPO among people with different types of thyroid diseases.Material and methods<p class="abstext...

Background: G3NETs demonstrate variable clinical behavior (Ki-67>20-100%). Treatment extrapolated from grade 1/2 (G1/2) NETs and neuroendocrine carcinomas depending on clinicopathologic features. Therapy for treatment-emergent G3NETs remains especially ill-defined.Methods: Retrospective chart review of patients with de novo G3NETs or progressing from low-to-high grade (L-H) (G1/2 at diagnosis and G3 >=3 months later). Treatment patterns compared ...

Intoduction: Pitiutary tumor is considered as the first etiology responsable of secondary hypopituitarism. Hypogonadotropic hypogonadism is the most commonly reported lesion.Meterials and methods: It is a retrospective study including 77 cases of prolactinoma. The data collection was done over 17 years, between 2000 and 2017.Results: Gonadotropic deficiency was confirmed in 48 patients (63.6%). A significant negative correlation wa...

Aim: The aim of the study was to evaluate the correlation between salivary and serum cortisol values to the healthy people and patients with Cushing’s syndrome.Methods: 33 cases: 21 healthy people aged 22 to 53 years old; 12 patients with Cushing’s syndrome values were included to our study. All the participiants of control group were healthy without known disease. Two samples of salivary and serum cortisol was taken to all the participiants of...

Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron and sodium and water homeostasis. Patients with hypothryoidism can have clinically important reductions in glomerular filtration rate (GFR). 41 patients (mean age 31.5±11 years) newly diagnosed as Hashimoto thyroiditis with presence of high thyroid autoantibodies with gland heterogenity in ultrasound and a...

Type 2 diabetes with poor glycemic control is a predisposing factor for periodontitis (Salvi et al. 2000). In this cross sectional study, subjects with type 2 diabetes (n=232, mean age: 50.08±3.2 years) were recruited with informed and written consent. Fasting plasma glucose, serum lipid profile and HbA1c was analysed by standardised methods. A complete dental examination for pocket depth, clinical attachment level and periodontitis was performed for all...

The objectives of this study were to assess the quality management system of 95 medical laboratories at regional and general hospitals under the jurisdiction of the office of the permanent secretary, Ministry of Public Health, Thailand, in relation to ISO 15189:2007 and determine the relationships between role perception, leadership and organization climate with medical laboratory quality management. This study was a cross-sectional study. Data were collected by self-assessmen...