Endocrine Abstracts

Aims: The aim of our study is to assess the efficacy of lifestyle modification in preventing diabetes mellitus type 2 (DM 2)Materials and methods: The study included 100 patients (69 m 258 f) 25–65 years with impaired glucose tolerance/impaired fasting glucose (IGT/IFG) and newly diagnosed DM 2. Patients were divided into two groups matched by sex, age, weight, BMI, waist-to-hip ratio (WHR). Research group included 54 patients who received and carri...

Disorders of sex development (DSD) is the matter of controversy on what should be the methods of treatment. One of the main problem is preservation of underdeveloped gonads. The issue of concern are especially patients with gonadal dysgenesis and Y chromosome (with presence of potential testes) (GD) and patients with androgen insensitivity (46,XY and underdeveloped testes) (AIS). It was confirmed by many studies that the risk of germ cell neoplasia (GCN) is high in these gonad...

Introduction: Many factors influence intensity and duration of exposure to ultraviolet, including geographic location, season, dietary intake, atmospheric conditions and the daily sunlight exposure. Study was performed to determine prevelance of hypovitaminosis in housebound elderly.Design: 41 people (22 men and 19 women) living in Konya Residantal Care (RC) were taken. Serum 25-OH vitamin D (VD) measured in winter and in summer. Results were evaluated b...

Aim: To identify clinical significance of enzymuria in early diagnosis of DN in children and adolescents with type I diabetes mellitus.Materials and methods: We examined 112 patients (47 males/55 females) with type I diabetes mellitus. By the DN severity the patients were divided into following groups: with normoalbuminuria (NAU) (n=47), with microalbuminuria (MAU) (n=44) and with marked proteinuria (MP) (n=19). Ten healthy sub...

Background: The issue of hypothyroidism effect on bone tissue is underinvestigated, due to the small number of studies. In addition, it’s not easy to determine the effect of reduced thyroid function on bone strength due to the fact that these patients are usually elderly and have many additional factors for the development of osteoporosis. The purpose of the study is to assess the status of bone mineral density (BMD) in men with hypothyroidism.Mate...

Background: Marriage is an integral part of Indian society. In spite of the large number of people with diabetes mellitus (DM) in India, India is not a diabetes-friendly society. The society suffers from lots of myths regarding diabetes and insulin use. This survey highlights perceptions of general population with regards to marriage, associated diabetes distress, and suggests potential solutions. If no one is ready to accept diabetics as a bride or groom for their children an...

Introduction: Metformin is the first line treatment of type 2 diabetes, but now has been reported to cause a decrease in level of Vitamin B12.The aim of the study is to describe the prevalence of vitamin B12 deficiency in adults with type 2 Diabetes Mellitus who were in treatment with metformin compared in those without diabetes.Material and Methods: Total number of patients were 130 between 16–84 years old. Mean age 54.2 &#1...

Aim of the study was to investigate the lymphocytes (lymph) subpopulations as a part of immune response in peripheral blood among the patients with Diabetes mellitus type 2 (DMT2).Patients and methods: A prospective, cross-sectional, comparative, ‘case-control’ study was conducted among 70 patients with DMT2. The levels of lymph subtypes[-general nonspecific T-lymph (CD3+); T-helper lymph (CD4+); T--cytotoxic lymph (CD8+), natural...

Aim: The levels of serum Selectins (P and E–Selectin), membrane potential and antioxidant vitamins were determined in diabetic patients attending General Hospital Owerri, Nigeria.Materials and methods: A case control study involving 600 persons living with diabetes between the ages of 20 and 60 years attending General Hospital Owerri. Also, 600 apparently healthy persons within the ages of 20 and 60 years served as control. Fasting venous blood was...

Introduction: Accident at the Chernobyl NPP (ChNPP) in Ukraine on the 26th of April, 1986 was followed by the intensive release of a wide range of radioactive elements with affinity to many endocrine tissues. The mentioned radioactive fallout resulted in both internal and external radiation exposure, among others, of the central endocrine structures of the human brain.Methods: We have conducted a retrospective analysis (20–25 years upon radiation ex...