Endocrine Abstracts

Aim: The levels of serum Selectins (P and E–Selectin), membrane potential and antioxidant vitamins were determined in diabetic patients attending General Hospital Owerri, Nigeria.Materials and methods: A case control study involving 600 persons living with diabetes between the ages of 20 and 60 years attending General Hospital Owerri. Also, 600 apparently healthy persons within the ages of 20 and 60 years served as control. Fasting venous blood was...

Introduction: Accident at the Chernobyl NPP (ChNPP) in Ukraine on the 26th of April, 1986 was followed by the intensive release of a wide range of radioactive elements with affinity to many endocrine tissues. The mentioned radioactive fallout resulted in both internal and external radiation exposure, among others, of the central endocrine structures of the human brain.Methods: We have conducted a retrospective analysis (20–25 years upon radiation ex...

Introduction: The effect of BMI on mortality amongst the elderly may be different from younger adults. Thus, this study aims to determine the relationship between BMI and its 5-year changes on all-cause and cause-specific mortality in the elderly.Methods: During 1992–1994, the Blue Mountains Eye Study recruited 3654 residents aged ≥49 years in Sydney, Australia. Of these, 75% of survivors returned for follow-up at 5 years. We initially examine...

Introduction: Hormonal therapy is part of an established treatment of gender identity disorder, however outcome data regarding mortality and morbidity are scant.Methods: A specialist center cross-sectional study in 193 transsexual women and 128 transsexual men (mean age 42.5 years) assessing physical health and incidence of possible treatment related adverse events compared to an age-matched female and male control group recruited from a population study...

Background and objective: There have been reported increase prevalence of hypogonadism in diabetic men compared to age matched non-diabetic men. The objective of this study was to assess the level of androgens in T2DM patients and non-diabetics and correlate it with erectile function and visceral adiposity.Methods: This was a cross-sectional comparative study of 160 male patients with T2DM (study subjects) and 80 age matched non-diabetics (control subjec...

Objective: Bariatric surgery has a marked effect on diabetes risk in the obese. The aim of this study was to evaluate weight-loss independent effects of gastric bypass on glucose and insulin levels over 10-years of follow-up.Research design and methods: A total of 2010 obese individuals received bariatric surgery in the Swedish Obese Subjects (SOS) study (376 patients underwent non-adjustable or adjustable banding, 1369 underwent vertical banded gastropl...

Myeloperoxidase (MPO), an enzyme of the innate immune system, exhibits pro-atherogenic effects and includes influence on oxidative damage to LDL- and HDL-cholesterol, and promotion of endothelial dysfunction.The aim: To investigate the disturbance of MPO in type 2 diabetic (T2D) patients depending on intensity of atherosclerosisMaterial and methods: We investigated 244 patients aged from 45 to 60 years (M±SD 54.0±4.63) in...

Introduction: An increase in thyroid diseases after the Chernobyl, mostly due to radioactive iodine, has been scientifically recognized. It is also known the effect of nitrate on iodine metabolism: being a competitive inhibitor of sodium-iodine symporter nitrate prevents iodide uptake by the thyroid and compromises thyroid hormone synthesis.The aim of the study was to investigate the incidence of thyroid and salivary glands’ abnormalities by ultraso...

Materials and methods: The study included 58 patients (50 female, 8 males) aged from 38 to 60 years, have received surgical treatment for GD with the period of follow-up after treatment for 2 to 10 years. The patients were divided into 2 groups depending on the initial level of TSH. In the first group (33 persons) included patients with low-normal level of TSH (0.4–2.5 mU/ml), the in second group (25 persons) with upper-normal level of TSH (2.6–4.0 mU/ml). An estimat...

Materials and methods: The study included 58 patients (50 female, 8 males) aged from 38 to 60 years, have received surgical treatment for GD with the period of follow-up after treatment for 2 to 10 years. The patients were divided into 2 groups depending on the initial level of TSH. In the first group (33 persons) included patients with low-normal level of TSH (0.4–2.5 mU/ml), the in second group (25 persons) with upper-normal level of TSH (2.6–4.0 mU/ml). Quality of...