Endocrine Abstracts

Peripheral 18-oxocortisol level could contribute to the detection of aldosterone-producing adenoma in patients with primary aldosteronism. However, peripheral 18-oxocortisol varies among such patients, which is a big drawback concerning its clinical application. We studied 48 cases of aldosterone-producing adenoma, 35 harboring KCNJ5 mutation, to clarify the significance of clinical and pathological parameters regarding peripheral 18-oxocortisol. Peripheral 18-oxocort...

The aim of investigation to study of optimization of treatment of women of childbearing age with metabolic syndrome.Material and methods: Under supervision were 20 women with a metabolic syndrome who applied for infertility in Center of Endocrinology from 2014–2015. The control group consisted of 20 women without obesity and without disturbances of the menstrual cycle. The age of patients ranged from 20 to 39 years and averaged 28.3±0.64 years....

Background: Acromegaly is a rare disease with a long and complex diagnostic pathway leading to a substantial diagnostic delay associated with an increased risk of comorbidities and psychosocial deterioration. Qualitative methods are the gold standard to explore patients’ perspectives, focusing on how individuals understand and report what they are experiencing. To the best of our knowledge, no qualitative study has yet examined the diagnostic pathway of subjects with acro...

Purpose: To assess the effect of radiation therapy (RT) in patients with acromegaly, depending on the age of the patients and the activity of the formation.Materials and methods: The object of the study was 50 patients (36 women and 14 men) with acromegaly who received gamma-therapy in a total dose of 45-60 Gr. The age of patients ranged from 29 to 77 years. By age, the patients were divided into 3 groups: 1st age group-29–44years old-23patients (46...

Introduction: Digital epidemiology uses digital data which was not generated with the primary goal of serving epidemiological research (Life Sci Soc Pol 2018; 14:1). Recently, time and geographical correlation was noted between Google Trends findings and the prevalence of coronary artery disease (JACC, 2018, 71:98). Furthermore, using Google Trends, we have noted that the search terms ‘fatigue/weakness’ were correlated with the terms ‘hypothyroidism/thyroiditis&...

Background: Differentiated thyroid carcinoma (DTC) has an excellent prognosis with a relatively low recurrent and mortality rate, but a small portion of DTC patients suffers from an aggressive form of the disease with tumor invasion and metastasis. Accurate identification of this group of DTC patients is of crucial importance to optimizing individualized DTC treatment. This study aimed to retrospectively investigate the clinicopathologic predictive factors of cervical lymph no...

Introduction: Given their prevalence of up to 5% of the general population, A discovery of an asymptomatic adrenal mass (incidentaloma) during the investigation of an unrelated condition is relatively common. The issue of crucial importance is the histopathological differentiation between benign lesions and malignant tumours of the adrenal gland.Objective: To evaluate the secretory or non-secretory profile and the benign and malignant nature of incidenta...

Introduction: Hypoglycaemia is the most serious side effect inherent in the search for good glycemic control in diabetic patients, which can be fatal and often cause significant physical and psychosocial morbidity.Aim: The aim of our study was to estimate the frequency of hypoglycaemia and to determine the factors associated with their occurrence.Methods: This was a retrospective descriptive study. The study is conducted in 200 dia...

Aim: The aim of the study was to investigate the clinical and hormonal effectiveness of different modes of suppressive cabergoline (CAB) therapy during 12 months in patients with prolactinoma.Subjects and methods: It was examined and underwent a 12 month course of treatment by selective dopamine agonist CAB in 61 patients with prolactinoma (PROL) (9 male/ 52 female) aged 16–66 years. There were 40 women with microPROL, 12 with macro&giant PROL; ...

Introduction: Follicular or vesicular cancers represent 5 to 10% of differentiated thyroid cancers (CTD) and are therefore the second leading cause of endocrine tumors after papillary thyroid cancer. They can be minimally or massively invasive, and thus represent a more aggressive histological type compared to the papillary. The aim of our work is to describe in our context the clinical and evolutionary features of thyroid tumors of vesicular origin.Mate...