Endocrine Abstracts

Background: Hypothyrosis is an atherosclerosis-promoted condition. On the other hand, nitric oxide (NO) has antiatherogenic cardioprotective properties. By some Doppler ultrasound parameters (intima-media complex thickness (IMCT) and systolic velocity (SV)), one can point out the level of atherosclerosis presence in cardiovascular system out of histopathology.We primarily determine NO levels in studied population and then examine their influence on menti...

Objective: An adequate thyroid function during pregnancy is essential for the normal brain development of the foetus, and some organochlorine compounds (OCs) can interfere with the thyroid system. The objective of the present study was to evaluate the association between exposure to some OCs and thyroid function in pregnant women from two different areas in Spain, as well as to investigate the potential confounding effect of iodine intake.Methods: Thyroi...

Introduction: The fetus is the most vulnerable to severe iodine deficiency and hypothyroidism during pregnancy. Severe iodine deficiency and hypothyroidism during pregnancy have long been known to be associated with neurologic deficits and mental retardation The effects of mild iodine deficiency and subclinical hypothyroidism are poorly known. The present study assesses the association between thyroid hormones and urinary iodine concentration (UIC) in healthy pregnant women an...

Objectives: Estimate the prevalence of of cardiovascular symptoms, to identify the main changes in echocardiography at Graves disease (GD) and their dynamic during treatment.Methods: Investigated 86 patients with GD. The functional class (FC) chronic heart failure (CHF) was determined according to the New York Heart Association (NYHA). All patients underwent echocardiography before treatment and after 3 months of euthyroid state.Re...

Purpose: To evaluate the effectiveness of a combined antihypertensive therapy in treating arterial hypertension (AH) in patients suffering from diabetes mellitus (Type 2 DM) on different stages of obesity.Materials and methods: 80 patients suffering from Type 2 DM and AH on different stages of obesity underwent a monitoring. Depending on the stage of obesity, the patients were divided into three groups. The groups were comparable by age, sex, AH stage. T...

Background: Extended life expectancy and increase in neuroimaging availability, lead to increase in incidence of pituitary adenomas (PA) diagnosed after the age of 70. Recognition of PA in the elderly may be challenging and delayed due to symptoms overlapping with aging and comorbidities.Objective: To investigate character and presenting symptoms of PA in patients diagnosed after the age of 70.Methods: 105 patients (7.9%) with PA d...

Background: Increased life expectancy and wider availability of neuroimaging lead to increase in diagnosis of acromegaly in elderly patients, after the age of 70. Delay in diagnosis is attributable to milder symptomatology, higher prevalence of comorbidities and symptoms overlapping with normal aging process.Objective: To investigate clinical characteristics, presenting symptoms, comorbidities and treatment modalities of acromegaly in patients diagnosed ...

Quality of life (QoL) of hypothyroid patients can be estimated by use of numerous instruments (GHQ12 and TQ20). By rank transformation of obtained answers, calculated QoL score further determined groups, named as no distress (0–15 patients.), minor distress (16–24 patients.) and major distress (≥25 patients.). Rank transformation can be performed through Likert 0–3 as well modified 0–4 model. To groups with distress, levo-thyroxine (L-T...

Introduction: The prevalence of adrenal incidentalomas (AI) and renal cysts increase with age. Depending on the study population age and sex, on average, both are prevalent with about 8 to 10% in subjects older than 50 years of age.Aim: We aimed to investigate the co-occurrence of AI and simple renal cysts.Methods: Our study included 970 subjects, 494 with AI – all evaluated in single centre, and 476 control group (CG) patien...

Background: Venous thromboembolism(VTE) is a well-known perioperative complication in patients with Cushing’s syndrome(CS) and may be preventable. A recent report highlighted that thromboprophylaxis management in patients with CS still varies considerably across Endo-ERN reference centers but the actual incidence of VTE and its management in individual patients is unclear.Aim: To collect epidemiological and clinical data of new cases of CS reported ...