Endocrine Abstracts

Background: Schwannoma (Sch) is a rare peripheral nerve sheath tumor comprised entirely of neoplastic Schwann cells. Adrenal Sch are extremely rare. Most adrenal Sch are incidental, and patients with Sch may not have any complaints. Here we present the clinical case of giant adrenal Sch, which caused hematuria and had indiscriminating organ origin on MRI.Clinical case: Woman, 58 y.o., was consulted by urologist because of painless macrohematuria. Abdomen...

Introduction: Condition of injected skin and subcutaneous tissue is assessed by visual inspection and palpation and it has only 10–15% diagnostic value. The standard ultrasonography comparison of symmetrical skin areas is not valuable as they are usually used for injections.Objective: We examined 143 patients, aged 43.3 ± 3.9 years, with DM duration of 6.5 ± 2.8 years, receiving basal-bolus insulin therapy.Methods: ...

Introduction: Hashimoto’s Encephalopathy (HE) is an autoimmune inflammatory disease of the brain associated with the production of antithyroid antibodies.Objective: A clinical case of treatment of severe autoimmune encephalopathy in combination with autoimmune thyroiditis and thyrotoxicosis is presented.Results: A 59-year-old woman was transferred to the intensive care unit diagnosed with thyrotoxic crisis. Objectively: serio...

Introduction: T2DM prevalence in Belarus is 3.489.5 per 100 thousand people, annual growth rate is 5–6%. STEPS study: in 2016–2017 the following risk factors prevailed: overweight and obesity (61.2%), dyslipidemia (36%), hypertension (50%); inactive lifestyle (78.2%). The study aim was to assess risk factors for metabolic disorders in a young healthy population. Objective. 253 people were examined: 22.1% of men and 77.9% of women under 40. Methods: We performed ant...

Purpose: Radiation-induced anterior pituitary hormone deficiencie is the most common long-term complications of successful cancer treatment. The aim of our study was to analyze thyroid status in young adults after radiotherapy in childhood and their relationship with dose of radiotherapy.Materials and methods: Thyroid function (TSH, free T4, free T3) and thyroid ultrasound were evaluated in 29 young adults with a history of radiotherapy for brain tumors ...

IntroductionThyrotropin-receptor antibodies (TRAb) play a key role in the pathogenesis of Graves’ disease (GD) and Graves’ orbitopathy (GO) and are important for the diagnosis of both diseases. Elevated levels of immunoglobulin E (IgE) and antinuclear antibodies (ANA) were also found in GD patients. Smoking is a risk factor for GD and GO development and GO progression. We aimed to assess the associations between TRAb, IgE and ANA, and the prese...

Cyclic Cushing’s syndrome (CCS) is a rare condition that involves recurring episodes of hypercortisolaemia, alternating with normocortisolemia at intervals ranging from a few days to several years. To diagnose CCS, it is necessary to demonstrate three cortisol peaks and two troughs. CCS is mostly seen in females and can be Adrenocorticotropic hormone (ACTH)-dependent or independent2. The common causes of CCS are Cushing’s Disease (55% ), ectopic ACTH syndrome (26%), ...

The pituitary adenylate cyclase-activating polypeptide (PACAP), isolated for the first time from hypothalamic extracts (Miyata et al. 1989), was localized in some peripheral tissues such as adrenal, gastrointestinal tract, ovary and testis (Arimura et al. 1991, Watanabe et al. 1992, Gathei et al. 1993, Shioda et al. 1994, Kononen et al. 1994). It was previously demonstrated that in the testis PACAP was involved in the steroidogenesis r...

Introduction: Schwannomas are tumors derived from myelin sheat of nerves which can displace and compress nerves causing pain, weakness and numbness. Very rarely they become malignant.Case report: Thirty-one years old patient was hospitalized at our Department to evaluate hypopituitarism. He was born at term by cesarean section, with hydrocephalus and did not start to breath spontaneously. A few months later, he was diagnosed with scoliosis thoracalis dup...

AI are incidentally discovered adrenal masses without any prior suspicions of adrenal disease. They are most frequently hormonally inactive, with arterial hypertension (AH) as a common finding.The aim was to determine upright and supine PR and ALD levels in patients with AI, normotensive and hypertensive.Two hundred and eight patients (148 women and 60 men, mean age 55.08±11.02 years, mean BMI 27.91±4.6 kg/m2) ...