Endocrine Abstracts

IntroductionLithium remains a first-line treatment for several mental disorders.Hypercalcaemia has been associated with long-term lithium treatment, yet it is often unrecognized. The manifestations of hypercalcaemia can develop insidiously and mimic psychiatric disturbances.CasesCase Report 1 – A 53-year-old Caucasian gentlemen referred by his GP following routine bloods with an adjusted calcium of 3.46 ...

According to WHO epidemiological data, there are more than 650 million obese people in the world, the medical and social significance of which is determined by the development and aggravation of insulin resistance. Accumulation of experience in the treatment of patients with COVID-19 infection has demonstrated that obesity and diabetes mellitus are important risk factors affecting the clinical severity of inflammatory disease - for impaired function of β-cells along with ...

According to modern concepts, stress hyperglycemia and diabetes mellitus (DM) are often found in hospitals and are associated with an increase in complications, length of hospitalization and mortality. The analysis of data on the COVID-19 pandemic indicates a worse prognosis and a high risk of hospital complications in patients with DM.Aim: The aim of the study was to evaluate clinical and laboratory parameters that can be used to predict an unfavorable ...

Both hyperglycemia and in-hospital hypoglycemia are associated with poor hospital outcomes and increased healthcare costs. The effect of hypoglycemia may be due to the severity of the infectious disease and the high incidence of comorbidity. The aim of the study was to study the possible relationship between the severity, duration and compensation of hyperglycemia with the course of Covid-19.Materials and methods: A retrospective analysi...

Introduction: The actual prevalence of early carbohydrate metabolic disorders is associated with persistent hyperglycemia and can only be detected by targeted screening.Objective: We examined 316 people aged 51.21(46.7;62.35) years, without DM.Methods: We determined the 10-year risk of T2DM according to the Findrisc scale, anthropometric data, lipid profile, glycemia and HbA1c level, linear dimensions of preperitoneal and subcuteno...

Introduction: The actual prevalence of early carbohydrate metabolic disorders is associated with persistent hyperglycemia and can only be detected by targeted screening.Objective: We examined 316 people aged 51.21(46.7;62.35) years, without DM.Methods: We determined the 10-year risk of T2DM according to the Findrisc scale, anthropometric data, lipid profile, glycemia and HbA1c level, linear dimensions of preperitoneal and subcuteno...

Introduction: Condition of injected skin and subcutaneous tissue is assessed by visual inspection and palpation and it has only 10–15% diagnostic value. The standard ultrasonography comparison of symmetrical skin areas is not valuable as they are usually used for injections.Objective: We examined 143 patients, aged 43.3 ± 3.9 years, with DM duration of 6.5 ± 2.8 years, receiving basal-bolus insulin therapy.Methods: ...

Objectives: To evaluate the quality of life (QoL) in patients with differentiated thyroid cancer (DTC) by a validated thyroid-specific questionnaire and to identify factors with significant impact on the QoL.Methods: Two hundred DTC patients, treated in one tertiary center, were recruited in the study. One year after the thyroid surgery, they completed the QoL Cancer Survivor Instrument – Thyroid version questionnaire. The questionnaire assessed the...

The anterior pituitary gland is a critical endocrine organ responsible for many important physiological processes including puberty, fertility, metabolism and the stress response. It is derived from, and maintained by, a population of SOX2+ progenitor/stem cells which become more quiescent with age until their direct contribution to tissue turnover becomes negligible. Previous research has demonstrated that the postnatal SOX2+ population exhibits heterogeneity in terms of mark...

Background: Combined oral contraceptives (COC) are known to have multiple beneficial effects besides contraception, but also cause some unwanted health outcomes. They interfere, for example, with metabolism, inflammation, hepatic protein synthesis and blood coagulation. COCs containing natural estrogens have recently been developed, yet little is known about their non-contraceptive effects compared to conventional COCs with ethinyl estradiol (EE). The aim of this study was to ...